Jeuveau Injections

Wrinkle Treatment in the San Diego Area

Dr. Melanie Palm is an expert in the use of Jeuveau injections to treat unwanted wrinkles including frown lines. Dr. Palm is one of the first physicians in the U.S. to provide this new competitor to Botox for patient use. She has assisted Evolus, the maker of Jeuveau, in an instructional video to teach other physicians across the U.S. on proper technique when administering treatment to patients. Dr. Palm offers this premium botulinum toxin type A treatment at her practice, which is located in Solana beach, CA, just north of San Diego.

What is Jeuveau?

Jeuveau (prabotulinumtoxinA-xvfs) is a highly purified form of botulinum toxin A, the same “active ingredient” in Botox CosmeticDysport, and Xeomin. Similar to Botox, Jeuveau is composed of the same 900 kDa protein but undergoes a different purification and drying process termed Hi-Pure technology.

Is Jeuveau Available in the U.S.?

Yes. Jeuveau was FDA-approved in February 2019 for injection of facial muscles to improve the appearance of moderate to severe frown lines between the eyebrows. Jeuveau is also approved in Canada under a different trade name.


What Makes Jeuveau Different from Botox?

Jeuveau was designed and positioned to be a premium competitor to Botox. In clinical studies, Jeuveau was found to soften the appearance of frown lines as well as Botox. This is called a “non-superiority” study. Jeuveau is different from Botox in that it undergoes a different purification process, as well as a different drying process. The vacuum drying process of Jeuveau has been shown to not damage the botulinum toxin protein. Therefore, it is theoretically possible that Jeuveau may have better potency to other wrinkles relaxers, aka neuromodulators.

Where Can Jeuveau Be Injected?

Jeuveau is FDA-approved on label for the temporary improvement of moderate to severe frown lines between the eyebrows. Similar to Botox, Dysport, and Xeomin, Jeuveau can be injected “off-label” by skilled physicians to treat unwanted wrinkles and overactive muscles over many areas of the face and neck. These include forehead lines, crow’s feet, bunny lines of the nose, wrinkles around the mouth, the lip flip, gummy smile, pebbly chin (peau d’orange), and neck bands (platysmal bands).

Jeuveau Injections FAQ

Yes. Jeuveau has been study over 5 clinical studies that included over 2100 patients. Two large-scale FDA-trials were required to demonstrate that Jeuveau was both safe and works for frown lines. Botulinum toxin type A products have been used for cosmetic treatment of facial wrinkles in millions of patients for nearly two decades.

The Jeuveau injection procedure is quick, easy, and painless and should be similar to past experiences with Botox, Dysport, or Xeomin injections. Dr. Palm utilizes techniques and equipment to create minimal discomfort during the procedure. A typical injection session with Jeuveau lasts only a few minutes.

Yes. There is no limitation to patients that have used other products to try out Jeuveau. It is likely that results will be quite similar although individual variability is possible.

No. Although some individuals may notice wrinkle relaxation within the first 24 to 48 hours, most patients see full effect from Jeuveau within 4 to 7 days following the injection procedure.

Jeuveau has a comparable duration to other neuromodulators such as Botox. Typical results last 3-4 months.

There is typically no downtime following treatment with Jeuveau. In terms of side effects, the product labeling is similar to that of Botox, Dysport, or Xeomin. Most patients have no side effects following treatment and Jeuveau like other toxins are deemed very safe by the FDA. The most common side effects are bruising, swelling, or pain at the site of Jeuveau injection. A small chance of headache, around 10%, is possible, but this is actually lower than patients receiving placebo (no Jeuveau) during the FDA-clinical trial. Like other neuromodulators, Jeuveau can have very rare side effects such as but not limited to eyelid drooping, difficulty swallowing, strained speech, or difficulty breathing.

Limitations or contraindications to Jeuveau are the same as for that of Botox, Dysport, or Xeomin. Individuals with an allergy to any part of Jeuveau or botulinum toxin type A treatment should not use Jeuveau. Patients with certain neuromuscular conditions such as ALS or Lou Gehrig’s disease, Lambert-Eaton syndrome and myasthenia gravis should avoid use. Jeuveau should not be injected in an area of active skin inflammation or infection. Alert your physician to any medications you may be taking as rarely some may cause interactions with the effect of Jeuveau.

Yes, Jeuveau can be combined with other procedures, occasionally on the same day. Some injectable filler treatments can be combined with toxin treatment. However, Dr. Palm generally recommends that light, laser, microneedling, chemical peels and other skin procedures be performed at a separate visit.

Prices for Jeuveau are comparable to Botox but vary by provider. At Art of Skin MD, patients are charged based on the amount of Jeuveau they receive. The strength of muscle movement and desired areas of treatment will determine the cost of the procedure. As the degree of improvement and effect of Jeuveau is highly dependent on the injector’s experience and understanding of the product, it is encouraged that Jeuveau is performed by a board-certified dermatologist skilled in advanced cosmetic procedures such as Dr. Palm.

If you are looking for a Jeuveau injection expert in the San Diego area to treat your unwanted wrinkles and frown lines, call Dr. Melanie Palm at 858.792.SKIN (7546) to schedule your appointment.