Restylane Kysse Lip Filler Injections

The New Lip Filler and Lip Lines Treatment in the San Diego Area

Dr. Melanie Palm is a noted expert in the use of non-surgical injectables – including Restylane Kysse lip filler – with offices in Solana Beach, CA just north of San Diego. She is a principal investigator on the clinical trial leading to FDA-approval of Restylane Kysse. as well as a physician trainer, advisory board member, and consultant for Galderma.

What is Restylane Kysse?

Restylane Kysse is a hyaluronic acid filler from the Restylane family of products. FDA-approved in April 2020 and released in May 2020, Restylane Kysse is used for lip enhancement and correction of upper lip lines. This hyaluronic acid gel filler has been approved and used in Europe and Canada for several years prior to its introduction stateside.

What is Dr. Palm’s experience with Restylane Kysse?

Dr. Palm is one of 14 U.S. physicians selected as a principal investigator to lead the phase III clinical trial for Restylane Kysse. This means she treated subjects with this lip filler in the study that led to FDA-approval. Dr. Palm serves as an Advisory Board member, clinical investigator, national speaker, and physician trainer for Galderma, the company that makes Restylane Kysse. This indicates she has been selected to educate other physicians on products use and safety, and that she has assisted in studies related to Galderma products.

Where can Restylane Kysse be used?

Restylane Kysse is approved for treatment around in and in the lip area. This new hyaluronic acid gel filler is used to correct perioral lip lines, enhance lip shape and structure, and improve the corners of the mouth.

What are the benefits of Restylane Kysse?

This is a great question. To answer this, a phase IV clinical study was conducted on patients desiring lip enhancement. Treatment with Restylane Kysse to the lip improved lip smoothness, texture and fine lines. Following treatment, lips had a measurable increase in redness, or a blushy glow. Finally, when partners (husbands/wives, girlfriends/boyfriends, etc.) were asked, they found Kysse lips felt natural and were more kissable.

How long does Restylane Kysse last?

Restylane Kysse is FDA-approved for up to 48 weeks duration. In the FDA clinical trial, approximately 2/3 of physicians and almost 80% of patients appreciated a noticeable improvement in the lips almost 1 year following treatment and a touch-up. It is important to note that the lips are a very active area (like around the month) and lip enhancement may last closer to 6-12 months in “real-life” use.

Does Restylane Refyne look natural in the lips?

Yes. Restylane Kysse integrates into the area of placement extremely well, lending this filler to a very natural result in expert hands. Dr. Palm tailors lip filler placement and selection to individual patient needs, always striving for lip enhancement that addresses aging changes, enhances beautiful features, and restores lip fullness, symmetry and proportion.

What makes Restylane Kysse different from other hyaluronic acid fillers?

Restylane Kysse is the third Restylane filler product to use XpresHAn technology. This technology imparts flexibility and structure to the filler. In an areas such as the lips, flexibility and support allows the filler to look natural with motion such as eating or talking. XpresHAn technology means that Restylane Kysse blends well with the lip tissue, and has long-lasting results. In the FDA trial, over 60% of study subjects had no side effects following placement of Restylane Kysse in the lips, and swelling is typically mild following injection.

What is XpresHAn technology and which products like Restylane Kysse use it?

Three Restylane products utilize XpresHAn technology to impart great flexibility and support in tissues of these hyaluronic acid fillers. The Restylane XpresHAn hyaluronic gel products are softer gel textures that allow excellent tissue integration of the filler, allowing natural expression and movement. This softness and movement is created by a proprietary linking process of the hyaluronic acid particles. The more cross-linked, the more supportive the filler. XpresHAn Restylane hyaluronic acid filler products inclue the following from least to most cross-linked:

Refyne: Lowest percentage of cross-linking (6%) in XpresHAn family and used for support of nasolabial folds and marionette lines in younger or thinner skinned-patients
Kysse: Middle percentage of cross-linking (7%) in XpresHAn family. It is FDA-approved for upper lip lines and the lips.
Defyne: Highest percentage of cross-linking (6%) in XpresHAn family and excellent for more robust support of deeper nasolabial folds and marionette lines.

How much downtime is there following Restylane Kysse treatment?

In Dr. Palm’s experience, there is typically mild to minimal swelling following Restylane Kysse placement in the lips. While individual results may vary, most patients experience minimal to mild swelling for a day or two. Most patients can resume daily social activities same day.

As with any injectable dermal filler, there is a chance of bruise. Dr. Palm may use a cannula technique to minimize this risk, and patients should avoid medications, supplements, and vitamins that thin the blood for one week prior to treatment.

Can Restylane Kysse be combined with other fillers or procedures?

Yes, Restylane Kysse is often used by Dr. Palm in conjunction with other fillers, skin tightening procedures, or light and laser based technologies to create a more enhanced outcome. Restylane Kysse may be used with other fillers to balance the face and restore lost volume, a process called a “liquid face lift.” Dermal fillers such as Restylane Kysse are well paired with neuromodulators such as Botox or Dysport, in order to relax overactive facial muscles and provide a lip flip. While Kysse rejuvenates and enhances the lip region, light and laser technologies such as IPL, fractional CO2 laser resurfacing, or ResurFX may be employed to eliminate unwanted brown spots, broken blood vessels, enlarged pores, or uneven skin texture and wrinkles. Finally, skin tightening treatments such as Ultherapy, Instalift, or Exilis are excellent complements to filler use with products such as Restylane Kysse.

What is the cost of Restylane Kysse?

The price of Restylane Kysse ranges by amount of lip restoration to be accomplished. Typical price ranges for Restylane Kysse placement by a well-trained dermatologist or plastic surgeon is approximately $700-$1000 per syringe, although prices may vary.

What is lip injection with Restylane Kysse like? Does Kysse hurt?

Lips are one of the more sensitive facial areas to address. However, Dr. Palm and her team take appropriate measures to minimize discomfort during lip treatment.

Discomfort is mild during Restylane Kysse filler placement. Restylane Kysse is supplied with lidocaine already mixed into the hyaluronic acid filler itself, making the area numb as the mouth area is treated. Dr. Palm cares about patient comfort, and she provides various other means of increasing patient ease during the procedure. Comfort measures include topical numbing, localized numbing blocks if desired (dental block), and an ice pack, which is also provided to the patient for home use. With these pain mitigating measures, Restylane Kysse treatment is well-tolerated.

What are the possible side effects of Restylane Kysse?

In the clinical trial, over 60% of patients receiving Restylane Kysse for lip enhancement had no side effects following treatment. Adverse events are typically mild in nature. The most common and expected possible side effects include swelling and bruising. Like any injectable filler, there is a chance of other possible side effects including pain or soreness at the injection site, or allergic reaction. Serious complications, such as vessel compromise, stroke, or blindness is exceedingly rare but theoretically possible.

Dr. Melanie Palm now offers Restylane Kysse lip filler injections. Get natural and beautiful lips with little swelling or downtime! Call 858.792.SKIN. Located in Solana Beach, CA just north of San Diego.