Exosome Innovation Meets Evidence-Based Beauty: Invo Aesthetics at Art of Skin MD
At Art of Skin MD, we believe in offering skin and hair rejuvenation options that are not only innovative but firmly rooted in science. For the first time ever, we are proud to introduce a regenerative skincare line featuring exosomes and growth factors that meets our highest clinical standards—Invo Aesthetics.
This is more than just another product launch. It’s the beginning of a new chapter in biologic skin care, where potent active ingredients derived from human fibroblasts, umbilical cord (Wharton’s Jelly), and bone marrow mesenchymal cells are used to reprogram skin from the inside out. Invo Aesthetics offers the highest concentration of exosomes and peptides available—and we’re excited to tell you why that matters.
“These are the first exosome-based products I’ve chosen to carry at Art of Skin MD—because the science, sourcing, and outcomes finally aligned.”
– Dr. Melanie Palm, Board-Certified Dermatologist & Invo Aesthetics Medical Advisory Board Member
What Are Exosomes—And Why Are They All the Buzz?
Exosomes are extracellular vesicles—tiny lipid bubbles—naturally secreted by cells. Think of them as cellular messengers or couriers. They’re loaded with:
- Growth factors
- MicroRNAs
- Cytokines
- Peptides
- Proteins
These contents are key to intercellular communication, modulating inflammation, stimulating repair, and promoting regeneration.
Why they matter in skincare
In recent years, exosomes have emerged as a gold-standard regenerative therapy, particularly in dermatology. Unlike growth factors alone, exosomes carry both the genetic and protein-building instructions to “wake up” tired skin cells, enhance collagen production, soothe inflammation, and reverse signs of aging.
| Feature | Exosomes | Growth Factors |
| Size | ~30–150 nm | ~10–50 kDa |
| Contents | Genetic RNA + Proteins | Proteins only |
| Function | Messaging + gene modulation | Stimulate repair |
| Longevity | Longer lasting, cell-derived | Less stable on skin |
Trending in aesthetics: Exosomes have become a rising star in microneedling, RF, and hair restoration protocols, showing faster healing, reduced inflammation, and amplified outcomes. However, many formulations on the market are poorly quantified, low-dose, or unregulated—until now.
Growth Factors: Skin’s Natural Rebuilders
Growth factors are proteins that tell your cells to grow, divide, and repair. Dermatologists have used topically applied growth factors for over a decade to stimulate fibroblasts, enhance collagen, and accelerate recovery from procedures.
Key growth factors in Invo products:
- KGF (Keratinocyte Growth Factor): Stimulates skin and hair follicle renewal
- sh-Oligopeptides: Signal healing and tissue regeneration
- sh-Polypeptides: Support fibroblast proliferation and collagen synthesis
What’s new?
Invo Aesthetics doesn’t just include growth factors—it pairs them with trillions of exosomes and over 1,200 peptides and proteins in a patented BioBlend™ delivery system, elevating their performance and stability.
The Invo Aesthetics Lineup: Potent, Proven, Transformative
Each product in the Invo suite was carefully selected for its high active concentration, clinical application, and cost-effectiveness—finally making regenerative skincare accessible without compromise.
- Rejuvenating Complex (RC) – At-Home Daily Defense
This elegant daily-use serum is your take-home miracle. With 1.2+ trillion exosomes and the full suite of 1,200+ growth factors and peptides, RC is designed to:
- Visibly reduce fine lines and wrinkles
- Improve elasticity and firmness
- Even skin tone and calm redness
- Defend against oxidative stress
- Reverses fine lines and wrinkles
- Strengthens skin barrier
- Boosts collagen & elasticity
- Antioxidant and anti-glycation protection
Available here online or in-clinic with special pricing!
- Rejuvenating Skin Solutions (RSS) – Post-Treatment Glow Booster
- Used post-laser, RF, and microneedling
- Reduces redness and downtime
- Enhances collagen remodeling
- Revives skin luminosity
Bioactives Include:
- Honeybee Defensin-1 & Niacinamide
- Sodium Hyaluronate
- Potent Peptide Complexes
Ideal for those seeking clinical-grade radiance with minimal downtime.
Delivered in-office immediately after treatment.
- Brightening Skin Solutions (BSS) – Target Pigmentation with Precision
For patients struggling with melasma, hyperpigmentation, or dullness, BSS is a powerful adjunct to laser and microneedling treatments. This precision product reduces melanin formation and visibly evens skin tone.
Key Clinical Benefits:
- Lightens dark spots
- Calms inflammation post-procedure
- Promotes even, glowing skin
Notable Actives:
- Tranexamic Acid
- Advanced Brightening Peptides
- Honeybee Defensin-1
- Niacinamide + Sodium Hyaluronate
Used with pigment correction therapies or melasma protocols.
- Advanced Hair Solutions (AHS) – For Thicker, Stronger Hair
AHS is a revolutionary scalp therapy used with hair restoration protocols including microneedling, PRP, and laser devices. With a synergistic blend of botanical DHT blockers, growth stimulants, and over 162 trillion exosomes, AHS:
- Nourishes scalp health
- Activates dormant follicles
- Strengthens the hair shaft
- Supports prolonged anagen phase
Featured Actives:
- Saw Palmetto: Natural DHT blocker
- KGF & Peptides HARIN I & II: Follicular stimulation
- Caffeine + Hyaluronic Acid: Circulation and hydration
Pairs with microneedling and PRP hair restoration.
Why Exosomes, Why Now?
Exosomes—nanoparticles naturally secreted by stem cells—are the next frontier in aesthetic medicine. They act as intercellular messengers, delivering genetic and protein instructions to repair, regenerate, and optimize tissue function.
Clinical Advantages of Exosomes Include:
- Enhanced collagen synthesis
- Immunomodulation to reduce redness and inflammation
- Faster healing with reduced downtime
- Amplified procedural outcomes
Until now, high-concentration exosome therapies were cost-prohibitive or lacked transparency. Invo Aesthetics changes that with science-forward pricing and formulations that outperform at a fraction of the cost.
At Art of Skin MD: How We Use Invo Aesthetics
We incorporate these exosome-rich solutions into our most cutting-edge aesthetic procedures:
In-Office Protocols:
- RSS: Used post-laser or RF microneedling to boost recovery and radiance
- BSS: Paired with pigment correction treatments for enhanced skin tone
- AHS: Applied post-scalp microneedling for hair regrowth stimulation
Skin Rejuvenation
Skin Rejuvenation
Hair Rejuvenation
At-Home Maintenance:
- RC: Integrated into your daily regimen to build on in-office results and rejuvenate skin long term
Why Invo Aesthetics Stands Above the Rest
There are dozens of “exosome” products on the market, but few reveal their true contents or concentration. In contrast, Invo Aesthetics:
- Uses FDA-cleared human tissue sources (umbilical cord, bone marrow, dermal fibroblasts)
- Contains quantified actives – 162+ trillion exosomes and 1,200+ bioactives
- Adheres to GMP manufacturing standards
- Features proprietary BioBlend™ conditioning for superior delivery
- Clinically validated and dermatologist-designed
Bonus: Cost-effective compared to leading competitors—without sacrificing quality or concentration.
How We Use It at Art of Skin MD
| Product | Use Setting | Indication |
| RC | At-home | Daily anti-aging maintenance |
| RSS | In-office | Post-laser, RF, or microneedling recovery |
| BSS | In-office | Brightening post-pigment treatment |
| AHS | In-office | Scalp rejuvenation with microneedling |
These are seamlessly incorporated into our protocols for laser resurfacing, chemical peels, microneedling, and hair restoration to amplify results and accelerate recovery.
Final Thoughts from Dr. Melanie Palm
“As a board-certified dermatologist and clinical researcher, I’ve long been intrigued by the promise of exosomes—but was waiting for a formulation that delivered results, transparency, and safety. Invo Aesthetics finally meets that mark. I’m thrilled to offer this next-generation regenerative skincare to our patients at Art of Skin MD.”
Visit Art of Skin MD or call us at (858) 792-7546 to schedule your Invo Aesthetics consultation and experience the future of skin and scalp rejuvenation—today.
